• CHAUHAN JIGARKUMAR VIPULSINH

GERD (Gastro Esophageal Reflux Disease) is a very common disease. People suffering in all age but more common after age of 40 Year. In India around 250 Million of people suffer from GERD. Proton pump inhibitors (PPI) are potent acid-suppressive agents which be can provide relief from symptoms of gastro esophageal reflux disease (GERD) and maintenance of health-related quality of life. Esomeprazole is good highly effective and used in monotherapy in GERD.esomeprazole having shorter half-life So, for the good therapeutic effect and improve bio availability need to be prolong drug release. Microsponges drug delivery system is highly cross link porous in nature and drug release in control manner from pores present on the surface of microsponges and release of drug without dose dumping.

GERD, Esomeprazole, Microsponges Drug Delivery, Quassi Emulsion Solvent Diffusion

"A Review on Esomeprazole Microsponges for GERD: A Novel Approach", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 6, page no.226-235, June 2019, Available :http://www.jetir.org/papers/JETIR1907A58.pdf

"A Review on Esomeprazole Microsponges for GERD: A Novel Approach", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 6, page no. pp226-235, June 2019, Available at : http://www.jetir.org/papers/JETIR1907A58.pdf