• Divya Thapliyal
• Meenu Chaudhary
• Praveen Kumar

An accurate, precise, and specific method developed for estimation of Quetiapine Fumarate in bulk. The API is used for the method development by UV spectroscopy with Ethanol: Water (50:50). The calibration curve method showed wavelength maxima for Quetiapine Fumarate at 295 nm with Ethanol: Water (50:50). This method obeys Beer’s law in the concentration range of 5-50µg/ml with correlation coefficient 0.999 for Quetiapine Fumarate. The precision results are not more than 2%. The LOD and LOQ were found to be 0.552 and 1.6728 respectively. The percentage assay of Quetiapine Fumarate in pharmaceutical dosage form was found to be 99.89%. The results of analysis have been validated in order to verify linearity, precision, and accuracy for the goal intended and further implementation for the quantification analysis in the pharmaceutical dosage form. The newly developed spectroscopic method is used for the routine analysis for Quetiapine Fumarate in pharmaceutical dosage forms.

Analytical Method, Quetiapine Fumarate, Validation, UV spectroscopy

"ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR ESTIMATION OF QUETIAPINE FUMARATE IN BULK AND PHARMACEUTICAL DOSAGE FORM", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 6, page no.967-974, June 2019, Available :http://www.jetir.org/papers/JETIR1907B61.pdf

"ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR ESTIMATION OF QUETIAPINE FUMARATE IN BULK AND PHARMACEUTICAL DOSAGE FORM", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 6, page no. pp967-974, June 2019, Available at : http://www.jetir.org/papers/JETIR1907B61.pdf