• Sathiya N
• Shajahan A
• Anusha N

Chitosan a deacetylated derivative of chitin has been reported for its various food and pharmacology industries. Chitosan was extracted from the fungal mycelia, Aspergillus niger. The physical-chemical nature of fungal chitosan was characterized by FTIR, MALDI-TOF and solid-state NMR with a 70.56% Degree of Deacetylation. Chitosan-mediated inhibition is affected by several factors included such as intrinsic, environmental, microorganism and physical state. Numerous studies presented chitosan with some biological properties such as antibacterial activity, antitumor activity, and antifungal activity paving the way to solid state forms such as beads, films, fibers, and hydrogels. Hence the present study was focused on preparation of chitosan based nanoparticle film were prepared using ionic gelation method followed by casting plate technique. SEM micrograph image showed the size of nanoparticles varied approximately from 200 nm to 400 nm. The films were further subjected for antibacterial action against Gram positive and Gram negative bacteria.

Antibacterial activity, Degree of Deacetylation, FTIR, Fungal chitosan, Nanoparticle film.

"Antibacterial Activity of Chitosan Based Nanoparticle Films Derived from Aspergillus niger", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 6, page no.975-987, June 2019, Available :http://www.jetir.org/papers/JETIR1907B62.pdf

"Antibacterial Activity of Chitosan Based Nanoparticle Films Derived from Aspergillus niger", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 6, page no. pp975-987, June 2019, Available at : http://www.jetir.org/papers/JETIR1907B62.pdf