• S.BAKKIALAKSHMI
• V.BARANI

The binding of Amantadine (AMT) to egg albumin (EA) in sodium lauryl Sulfate (SLS) solution was investigated by molecular spectroscopy at pH 7.4. The steady-state fluorescence, time-resolved fluorescence and UV – absorption spectroscopies were employed to study the mode and the mechanism for this interaction. Amantadine binding is characterized by one by high affinity binding site with the binding constant of the order of 105. The micelle parameters have been calculated and tabulated. FTIR spectra and SEM photographs have also been used to know the formation of complex of Egg albumin and Amantadine in SLS solution.

Amantadine, Egg albumin, fluorescence spectra, UV absorption spectra, Sodium lauryl sulphate.

"INTERACTION OF AMANTADINE WITH EGG ALBUMIN IN SLS : SPECTROSCOPIC STUDIES", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 6, page no.312-324, June 2019, Available :http://www.jetir.org/papers/JETIR1907C06.pdf

"INTERACTION OF AMANTADINE WITH EGG ALBUMIN IN SLS : SPECTROSCOPIC STUDIES", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 6, page no. pp312-324, June 2019, Available at : http://www.jetir.org/papers/JETIR1907C06.pdf