• SONI KUMARI
• RAJESH KUMAR
• VIBHUTI NARAYAN SINGH

Objective: To evaluate the effects of Carica papaya seed extract on seminal protein concentration in male mice. Methods: 60 adult male Swiss albino mice were divided into two groups: group 1st (treated group) was fed 0.1 ml of Carica papaya seed extract (50 mg/kg body wt.) while group 2nd (control group) was fed same amount of distilled water with similar exposure. After 10 to 50 days of treatment mice were sacrificed. Semen samples were collected from cauda epididymis of both groups of the mice. These samples were filtered, centrifuged and processed for electrophoresis. Results: Results showed that papaya seed extract mainly induced the anodic protein concentration in semen of treated group of mice than the control. However, cathodic protein concentration increased insignificantly than the control. Due to increase in anodic protein concentration, total electrophoretic protein concentration of treated group of mice also increased significantly (P<0.001) after 10 to 50 days of treatment than the control. Conclusion: Increase in anodic protein concentration in semen of treated group of mice may add more negative charge on the sperm surface membrane which may inhibit capacitation as well as fertilizing ability of the spermatozoa.

Anodic protein, Cathodic protein, Semen, Antifertility, Relative mobility

"Antifertility effects of aqueous seed extract of Carica papaya Linn. on seminal electrophoretic proteins of mice (Mus musculus).", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 6, page no.758-762, June 2019, Available :http://www.jetir.org/papers/JETIR1907C68.pdf

"Antifertility effects of aqueous seed extract of Carica papaya Linn. on seminal electrophoretic proteins of mice (Mus musculus).", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 6, page no. pp758-762, June 2019, Available at : http://www.jetir.org/papers/JETIR1907C68.pdf