UGC Approved Journal no 63975

ISSN: 2349-5162 | ESTD Year : 2014
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Published in:

Volume 6 Issue 9
September-2019
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR1907D83


Registration ID:
221794

Page Number

588-603

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Title

Biostatistics: A Revolutionary Approach For Optimization Of New Drug Formulation And Development

Abstract

Design of Experiments (DoE) have been widely used to understand the effects of multidimensional and interactions of input factors on the output responses of pharmaceutical products and analytical methods. It is always important before beginning experimentation to determine the objective of an experiment, and this is no different with DoE. Identifying objectives helps focus a team on its specific aims (scientific understanding of the task/problem in hand) over a period of time. It has been suggested that DoE can offer returns that are four to eight times greater than the cost of running the experiments in a fraction of the time that it would take to run one-factor-at-a-time experiments .This review shows about the principles and applications of the most common screening designs, such as two-level full factorial, fractionate factorial, and Plackett-Burman designs; and optimization designs, such as three-level full factorial, central composite designs (CCD), and Box-Behnken designs. DoE studies in support of QbD are often a delicate balance between delivering defined, high-quality products and meeting predetermined time, labor, and financial constraints. Statistical terms and procedure were found in nearly all of the research articles published. Thus, pharmacy education should aim to provide current and future pharmacists with an understanding of the common statistical terms and procedures identified to facilitate the appropriate appraisal and consequential utilization of information.

Key Words

Design of Experiments (DoE), Statistics, Biostatistics, Experimental designs., Applications of Statistics and DoE

Cite This Article

"Biostatistics: A Revolutionary Approach For Optimization Of New Drug Formulation And Development", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 9, page no.588-603, September 2019, Available :http://www.jetir.org/papers/JETIR1907D83.pdf

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2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"Biostatistics: A Revolutionary Approach For Optimization Of New Drug Formulation And Development", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 9, page no. pp588-603, September 2019, Available at : http://www.jetir.org/papers/JETIR1907D83.pdf

Publication Details

Published Paper ID: JETIR1907D83
Registration ID: 221794
Published In: Volume 6 | Issue 9 | Year September-2019
DOI (Digital Object Identifier):
Page No: 588-603
Country: MEHMEDABAD, Gujarat , India .
Area: Pharmacy
ISSN Number: 2349-5162
Publisher: IJ Publication


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