UGC Approved Journal no 63975(19)

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Published in:

Volume 4 Issue 1
January-2017
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR1907E14


Registration ID:
221520

Page Number

94-106

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Title

ISOLATION AND CHARACTERIZATION OF ACTIVE COMPOUNDS PRESENT IN THE METHANOLIC FRUIT EXTRACT OF TERMINALIA CHEBULA

Abstract

Consumption of Terminalia chebula fruit as food additive has become important in the promotion of human health, mainly due to their antimicrobial and other biological activities. Consequently, there has been a growing interest in identifying natural antioxidants and antimicrobials from these plants. This study aimed to characterize the phytochemical constituents of T. chebula which reveals the presence of alkaloids, terpenoids, flavonoids, tannins, glycosides, steroids and phenolic compounds. HPTLC profile showed the presence of five polyvalent phyto constituents, and the Rf value of the highest concentration of the phytoconstituents (36.56%) was found to be 0.89. Based on the purity and yield, three compounds were obtained with Rf values 0.57, 0.52 and 0.47. Compound 2 showed good inhibitory activity against the cariogenic organisms tested and was further selected for structure elucidation. The IUPAC name of compound 2 was found to be 3,8-dihydroxy-2,7-dimethoxychromeno[5,4,3-cde]chromene-5,10-dione. The chemical formula was C16H10O8 and the exact mass was found to be 330.04, thus the molecular weight was 330.04. The present finding indicates the presence of new derivative of ellagic acid in the methanolic fruit extract of T. chebula and it might be a promising compound for the development of antimicrobial agent against oral pathogens in humans.

Key Words

T. chebula, cariogenic organisms, phytochemicals, metabolite profiling, structure elucidation.

Cite This Article

"ISOLATION AND CHARACTERIZATION OF ACTIVE COMPOUNDS PRESENT IN THE METHANOLIC FRUIT EXTRACT OF TERMINALIA CHEBULA", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.4, Issue 1, page no.94-106, January 2017, Available :http://www.jetir.org/papers/JETIR1907E14.pdf

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2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"ISOLATION AND CHARACTERIZATION OF ACTIVE COMPOUNDS PRESENT IN THE METHANOLIC FRUIT EXTRACT OF TERMINALIA CHEBULA", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.4, Issue 1, page no. pp94-106, January 2017, Available at : http://www.jetir.org/papers/JETIR1907E14.pdf

Publication Details

Published Paper ID: JETIR1907E14
Registration ID: 221520
Published In: Volume 4 | Issue 1 | Year January-2017
DOI (Digital Object Identifier):
Page No: 94-106
Country: -, -, - .
Area: Engineering
ISSN Number: 2349-5162
Publisher: IJ Publication


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