• D.LEEMA ROSE MARY
• Dr. P. MARIE AROCKIANATHAN
• N.PRIYA
• D.VANITHA
• S Kulandai Samy

ABSTRACT The plant Sauropus androgynus belongs to the family Euphorbiaceae is known to exhibit various pharmacological activities like anti-oxidants, anti-arthritic and anti-cancer activity. The preliminary phytochemical screening showed the presence of alkaloid, phenol, saponin, tannin, phytosterol and flavonoids respectively. The antioxidant capacities of the ethanolic extract were studied using DPPH method. The result showed that the plant S.androgynus exihibited significant antioxidant properties. Invitro anti-arthritic activity of protein denaturation method showed maximum percentage of inhibition at 250µg/ml concentration compared with the standard drug. The ethanolic extracts of S. androgynus showed the inhibited the cell proliferation by more than 97% at its maximum concentration, while there was no effect on the growth of normal cells. Such selective effects were found to be time dependent. The present study reveals the presence of active constituents in the leaves. In addition to it, the leaves were exhibited effective antioxidant, anti-arthritic and anti cancer activity against breast cancer cell lines (MCF7). Thus this study of ethanolic extract of S. androgynus leaves can be a breakthrough for further studies. Keywords: MCF7 cancer cell, Sauropus androgynus, anti-arthritic, antioxidant

MCF7 cancer cell, Sauropus androgynus, anti-arthritic, antioxidant

"ANTIOXIDANT ANTICANCER AND ANTI-ARTHRITIC ACTIVITY OF ETHANOLIC EXTRACT OF SAUROPUS ANDROGYNUS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 6, page no.139-146, June 2019, Available :http://www.jetir.org/papers/JETIR1907K20.pdf

"ANTIOXIDANT ANTICANCER AND ANTI-ARTHRITIC ACTIVITY OF ETHANOLIC EXTRACT OF SAUROPUS ANDROGYNUS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 6, page no. pp139-146, June 2019, Available at : http://www.jetir.org/papers/JETIR1907K20.pdf