• Dr. Shams ul Nisa
• Dr.Namrata Harchandani
• Dr. Shameeka Thopte

Background:The term apitherapy is a branch of alternative medicine used to denote a form of medicine (honey) that falls in the main stream of western countries. The various allopathic and traditional remedies have been tried in aphthous ulcer. In this open label trial study, the aim was to observe the effectiveness of a novel topical agent honey on recurrent aphthous stomatitis. Material and method: The present study was conducted on 400 patients diagnosed to have recurrent minor aphthous ulcers. The baseline parameters which were recorded on the first visit includenumber of ulcers, size, pain, erythema, exudation and recurrence. Patients with increased frequency of stomatitis were advised to use 100% natural honey for three to four times daily till ulcer heals. The changes in parameters were observed and recorded on each visit of the patient.The efficacy and safety evaluations were made on the 2nd and 3rd Visit (3rd and 6thday). Patients were followed for a period of 1 year and thenumber of ulcers per month wasrecorded to evaluate for recurrence rate. Results: The erythema, exudates and pain in the ulcer started to reduce in 2-3 days. The size of ulcer started to reduce in almost 2nd visit (3rd day) and complete resolution seen on 3rd visit (6th day). There was no recurrence in any case till 1 year of treatment. Conclusions: Honey showed complete resolution of recurrent aphthous stomatitis due to antimicrobial, antibacterial, anti-inflammatory and antioxidant effect.

Recurrent Aphthous Ulcer, Honey, Aphthous Minor.

"Apitherapy: A Holistic Agent in Canker Sore", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 6, page no.492-500, June 2019, Available :http://www.jetir.org/papers/JETIR1907M64.pdf

"Apitherapy: A Holistic Agent in Canker Sore", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 6, page no. pp492-500, June 2019, Available at : http://www.jetir.org/papers/JETIR1907M64.pdf