• K. Nandini
• Y. B. Basavaraju
• N. K. Hemanth Kumar

A new class of pyrazole analogues was synthesized by three step reaction in good yields. Initially selected chalcones were treated with hydrazine hydrate in alkali medium through claisen condensation reaction. Further, chloroacetyl pyrazoline derivatives were synthesized by condensation of pyrazoline derivatives with chloroacetyl chloride followed by coupling of different secondary amines afforded target compounds. The structures of newly synthesized compounds were confirmed by IR, 1H NMR, 13C NMR, and MASS as data. The synthesized compounds were screened for their biological activities.

Pyrazole, chalcone, antibacterial activity and antifungal activity.

"SYNTHESIS AND PHARMACOLOGICAL STUDIES OF NEW PYRAZOLE ANALOGUES", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 6, page no.975-980, June 2019, Available :http://www.jetir.org/papers/JETIR1907Q45.pdf

"SYNTHESIS AND PHARMACOLOGICAL STUDIES OF NEW PYRAZOLE ANALOGUES", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 6, page no. pp975-980, June 2019, Available at : http://www.jetir.org/papers/JETIR1907Q45.pdf