• Baseerat Hamza
• Menka Surana
• kanury.V.S.Rao

Amid the most recent decade, protein analysis and proteomics have been built up as new devices for understanding different biological issues. As the distinguishing proof of proteins after classical separation strategies, for example, two-dimensional gel electrophoresis, have turned out to be standard techniques, new difficulties emerge in the field of proteomics. There is a critical need to scan for biomarkers that are characteristic of neurodegenerative Diseases, as the clinical diagnosis of which stays unsuitable. Mass spectrometry (MS) has been assuming an imperative part in considering peptide and protein identities, structures, modifications and interactions that aggregately drive their biological functions. MS-based proteomics innovation is along these lines appropriate for the biomarker revelation. In this article we discussed about the method, of proteomics-based mass spectrometry, Proteome Quantification Methods, functions, Comparison of performance characteristics of commonly used mass spectrometers for proteomics, we also reviewed the workflows or Process employed for biomarker discovery and recent functions of MS-based proteomics etc.

label based,Mass Spectrometry,Metabolically,Proteomics,Silac

"IMPLICATIONS OF MASS SPECTROMETRY FOR PROTEOMICS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 6, page no.683-689, June 2019, Available :http://www.jetir.org/papers/JETIR1907S08.pdf

"IMPLICATIONS OF MASS SPECTROMETRY FOR PROTEOMICS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 6, page no. pp683-689, June 2019, Available at : http://www.jetir.org/papers/JETIR1907S08.pdf