• Dr.Esha Shrestha
• Dr. Sabin Rajbhandari
• Dr. Sourav Manna
• Dr.Dayaram Ghimire
• Mr. Anirban Majumder

Rate Pressure Product, a product of Heart Rate and Systolic Blood Pressure, is a good index of Myocardial Oxygen Consumption. Increased myocardial oxygen consumption is the good indicator of increased myocardial oxygen demand. The objective of study is to find out the effect of mental stress on heart rate, blood pressure and rate pressure product in coronary artery disease patients and in their age-matched normal counterparts. After necessary instructions, blood pressure and heart rate were recorded before and immediately after standardized mental stress (mental calculation for a minute) and rate pressure product was calculated among the volunteers (n=150, 75 coronary artery disease patients and 75 control, age 40-80 years) and then analyzed. The result of the study showed mental stress induced rise in rate pressure product in both the groups (Coronary artery disease: 17.77% and control: 9.88% from the baseline). Nevertheless, mental stress induced increase in rate pressure product in patients exhibited higher than that of their aged-matched normal counterparts, indicating increased oxygen demand in the former group. From this we conclude that the measurement of rate pressure product (casual and mental stress induced) may help the clinicians to predict/screen coronary artery disease, especially the silent ones, and can prevent sudden anginal pain in them.

Blood Pressure, Coronary artery disease, Heart Rate, Mental stress, Rate Pressure Product

"Effect of Mental Stress on Rate Pressure Product in Patients Having Coronary Artery Disease and in Age Matched Normal Individuals.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 6, page no.188-195, June-2019, Available :http://www.jetir.org/papers/JETIR1907S96.pdf

"Effect of Mental Stress on Rate Pressure Product in Patients Having Coronary Artery Disease and in Age Matched Normal Individuals.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 6, page no. pp188-195, June-2019, Available at : http://www.jetir.org/papers/JETIR1907S96.pdf