• Aparna.p
• Dr. Brahma srinivasa rao
• k.indira

: Hyperlipidemia is a disorder of elevated levels of plasma concentrations of the various lipid and lipoprotein fractions, which is the key risk factor for cardiovascular disorders (CVD). Since synthetic drugs have been shown to have several side effects, clinical importance of the herbal drugs in treatment of hyperlipidemia has received considerable attention in recent years. Psidum guajava, carica papaya and cinnamomum verum are traditionally used as antihyperlipidemic drugs as per ayurvedic literature .Hence the present study was undertaken to investigate the antihyperlipidemic effect of a polyherbal formulation, prepared using the above three medicinal plants against Triton X-100 and Fructose diet induced hyperlipidemia in rats. ethanolic extract of the polyherbal formulation at 200 and 400 mg/kg dose inhibited the elevation of serum cholesterol and triglyceride levels and increase high density lipoprotein levels in hyperlipidemic rats. The extract also shows antioxidant activity. Thus the ethanolic extract of polyherbal formulation at the dose of 400mg/kg; p.o. showed good antihyperlipidemic activity in Triton X-100 and fructose diet induced hyperlipidemic rats. The above results propose that this Polyherbal formulation may be a potential source for the development of the new antihyperlipidemic drug.

Antihyperlipidemic activity, Polyherbal formulation, Triton X-100 and fructose diet.

"Assessment of Anti-hyperlipidemic and anti-oxidant activity of polyherbal formulation(BA019)", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 6, page no.88-96, June 2019, Available :http://www.jetir.org/papers/JETIR1908165.pdf

"Assessment of Anti-hyperlipidemic and anti-oxidant activity of polyherbal formulation(BA019)", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 6, page no. pp88-96, June 2019, Available at : http://www.jetir.org/papers/JETIR1908165.pdf