• S. Raj Arul Mercy
• M.K. Ismath Jahan

This present study was evaluates the antibiotic susceptibility pattern of Staphylococcus aureus isolates from clinical sample in around Salem area, Tamilnadu, India. A total of 25 clinical samples of pus, sputum, urine and blood was collected and subjected to isolation of as Staphylococcus aureus using selective media and biochemical tests. Disc agar diffusion method was used for the antibiotics resistance test. Our findings showed that 64% of the isolates were resistance to vancomycin and 56% for oxacillin followed by Tetracycline and Gentamycin (44%). The isolates were 100% sensitive to neomycin and cefoxidime. Presently 13 types of antibiotic resistance patterns were observed, among them, TE, NV, VA pattern was frequently observed in 20% of isolates. Furthermore, 56% biofilm producers were carried out by CRA method, which isolates had highest antibiotic resistance especially vancomycin and oxacillin. The early identification and select efficient control protocol against biofilm forming VRSA can be one of the important steps towards the prevention of the most serious nosocomial infections

S.aureus, VRSA, Oxacillin, Biofilm

"Antibiotic resistance and biofilm production among the isolates of Staphylococcus aureus isolated from clinical samples in Salem, Tamil nadu, India", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 6, page no.96-99, June 2019, Available :http://www.jetir.org/papers/JETIR1908319.pdf

"Antibiotic resistance and biofilm production among the isolates of Staphylococcus aureus isolated from clinical samples in Salem, Tamil nadu, India", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 6, page no. pp96-99, June 2019, Available at : http://www.jetir.org/papers/JETIR1908319.pdf