• N.Vijayalakshmi
• Inti.pavani
• sakala.srinija
• perli.mounika
• Namburi Raja kumari

The resistance towards available drugs is rapidly becoming a major worldwide problem. The need to design new compounds to deal with this resistance has become one of the most important areas of research today. Carbazole is a versatile moiety that exhibits a wide variety of biological activities. Review of literature says it is known that 1,2,3,4 – tetra hydro Carbazole are screened for enormous biological and pharmacological activities’s , still need for developing new derivatives at sslead compounds level. Although there is availability of new technologies such as high – throughput screening, combinational technology, microwave assisted synthesis and computer aided drug design, for multitude of new safety requirements that have arisen has also brought unanticipated hurdles for the task of translating in vitro to in vivo studies. In the view of that synthesis of 1,2,3,4 – tetra hydro carbazole derivatives to explore as potential Anti –microbial active compounds still draw continuous interest in molecular manipulations of active moieties with ensure to obtain drugs of high potency with low toxicity.

1,2,3,4-tetra hydro carbazoles,Anti –microbial active compounds.

"DESIGN SYNTHESIS AND EVALUATION OF ANTI MICROBIAL ACTIVITY ON A NEW SERIES OF 1,2,3,4- TETRA HYDRO CARBAZOLES", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 6, page no.261-266, June 2019, Available :http://www.jetir.org/papers/JETIR1908504.pdf

"DESIGN SYNTHESIS AND EVALUATION OF ANTI MICROBIAL ACTIVITY ON A NEW SERIES OF 1,2,3,4- TETRA HYDRO CARBAZOLES", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 6, page no. pp261-266, June 2019, Available at : http://www.jetir.org/papers/JETIR1908504.pdf