UGC Approved Journal no 63975

ISSN: 2349-5162 | ESTD Year : 2014
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Published in:

Volume 6 Issue 6
June-2019
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

7.95 impact factor calculated by Google scholar

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Published Paper ID:
JETIR1908B13


Registration ID:
227258

Page Number

89-95

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Title

Synergistic effect of Aloe vera and Vitamin C in regulating the steroidogenic and spermatogenic abnormalities of streptozotocin induced male diabetic rats.

Abstract

Diabetes mellitus is potentially affecting directly or indirectly, various functions of the reproductive system. Aloe vera extract is an effective agent in ameliorating the oxidative stress found in diabetes. Vitamin C, or ascorbic acid, is an important antioxidant substance in biological systems. The purpose of this study was to investigate the synergistic effects of Aloe vera extract and Vit.C on spermatogenic and steroidogenic activities of diabetic induced male rats. Aloe vera leaf gel extract, Vit.C and a mixture of both administered to three groups of male wistar strain albino rats for 30 days. Then the activity levels of 3-β HSD, 17-β HSD and Androgen dependent enzymes and the levels of hormones like Testosterone, FSH and LH were analysed. The diabetic rats treated with Aloe vera leaf gel extract in combination with Vit.c exhibited increased activity levels of 3-β HSD, 17-β HSD and androgen dependent enzyme activities when compared to other groups. Analysis of testosterone, FSH and LH levels has shown that the levels these hormones increased in the group that treated with mixture of both Aloe vera and Vit.c. According to the results of this study, the mixture of Aloe vera and Vit.C has good potential in increasing the steroidogenesis and spermatogenesis in diabetic induced male rats.

Key Words

Diabetes, Steroidogenesis, Spermatogenesis, Aloe vera, Vitamin C, Testosterone, FSH, LH, 3-β HSD, 17-β HSD.

Cite This Article

"Synergistic effect of Aloe vera and Vitamin C in regulating the steroidogenic and spermatogenic abnormalities of streptozotocin induced male diabetic rats.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 6, page no.89-95, June 2019, Available :http://www.jetir.org/papers/JETIR1908B13.pdf

ISSN


2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"Synergistic effect of Aloe vera and Vitamin C in regulating the steroidogenic and spermatogenic abnormalities of streptozotocin induced male diabetic rats.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 6, page no. pp89-95, June 2019, Available at : http://www.jetir.org/papers/JETIR1908B13.pdf

Publication Details

Published Paper ID: JETIR1908B13
Registration ID: 227258
Published In: Volume 6 | Issue 6 | Year June-2019
DOI (Digital Object Identifier):
Page No: 89-95
Country: SRIKALAHASTI, ANDHRA PRADESH, India .
Area: Biological Science
ISSN Number: 2349-5162


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