• Mr. Vivek Jain
• Dr. Neetesh K. Jain

Omeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).It works by decreasing the amount of acid made in the stomach.Omeprazole can be used in the treatment of gastro esophageal reflux disease (GERD), peptic ulcers, erosive esophagitis, Zollinger-Ellison syndrome, and eosinophilic esophagitis. amoxicillin, a semisynthetic antibiotic, Amoxicillin is an analog of ampicillin, with a broad spectrum of bactericidal activity against many Gram-positive and Gram-negative microorganisms. Amoxicillin is used to treat many different types of infection caused by bacteria, such as tonsillitis, bronchitis, pneumonia, and infections of the ear, nose, throat, skin, or urinary tract.Amoxicillin is also sometimes used together with another antibiotic called clarithromycin (Biaxin) to treat stomach ulcers caused by Helicobacter pylori infection.Rifabutiin is a broad-spectrum antibiotic that inhibits DNA-dependent RNA polymerase activity in susceptible cells. It is bactericidal and has a very broad spectrum of activity against most gram-positive and gram-negative organisms (including Pseudomonas aeruginosa) and specifically Mycobacterium tuberculosis. The present review article represents the compilation and discussion of analytical methods published in the literature for estimation of Omeprazole, Amoxicillin And Rifabutinin pharmaceutical samples and biological matrices consisting of HPLC, Stability indicating HPLC, UV-Visible method, Colorimetric method, Bioanalytical method, and hyphenated techniques such as LC-MS; LC-MS-MS, etc.

Keywords: Amoxicillin, Omeprazole, Rifabutin, UV Spectrophotometry, HPLC and LC-MS/MS

"A REVIEW ON ANALYTICAL METHODS FOR ESTIMATION OF OMEPRAZOLE, AMOXICILLIN AND RIFABUTIN IN PHARMACEUTICAL FORMULATIONS ANDBIOLOGICAL MATRICES", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 6, page no.54-65, June-2019, Available :http://www.jetir.org/papers/JETIR1908C10.pdf

"A REVIEW ON ANALYTICAL METHODS FOR ESTIMATION OF OMEPRAZOLE, AMOXICILLIN AND RIFABUTIN IN PHARMACEUTICAL FORMULATIONS ANDBIOLOGICAL MATRICES", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 6, page no. pp54-65, June-2019, Available at : http://www.jetir.org/papers/JETIR1908C10.pdf