• Shreekant Naik
• Pooja Prajapati
• Komal Jarhad

Barbituric acid is the paternal compound of barbiturate medications, while barbituric acid pharmacologically is inactive. Adolf von Baeyer was the first one who produced these compounds and can be involved in Knoevenagel type condensation reaction. Barbituric acid used as a reactant to from a large class of barbiturate drugs which are used as hypnotics, sedatives, anaesthetics and as central nervous system. Due to applications of barbiturates, exploration of new focus for the synthesis of these compounds is axiomatic. Thus, we selected way of green chemistry followed by grinding method along with aryl aldehyde treating with barbituric acid to get products, further these derivatives have been treated with metal salts to examine their ligand-metal connections under reflux conditions, antibacterial properties demonstrated the future scopes of these metal complexes.

barbituric acid, aryl aldehyde, grinding, IR, UV-Vis spectroscopy.

"SYNTHESIS, UV-VIS, IR SPECTRAL AND ANTIBACTERIAL ANALYSIS OF 5–ARYLIDENE BARBITURIC ACID DERIVATIVES AND THEIR METAL COMPLEXES", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.6, Issue 6, page no.196-202, June-2019, Available :http://www.jetir.org/papers/JETIR1908C25.pdf

"SYNTHESIS, UV-VIS, IR SPECTRAL AND ANTIBACTERIAL ANALYSIS OF 5–ARYLIDENE BARBITURIC ACID DERIVATIVES AND THEIR METAL COMPLEXES", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.6, Issue 6, page no. pp196-202, June-2019, Available at : http://www.jetir.org/papers/JETIR1908C25.pdf