UGC Approved Journal no 63975(19)

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Published in:

Volume 7 Issue 1
January-2020
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR2001015


Registration ID:
226770

Page Number

97-100

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Title

CORRELATION OF OVERACTIVE BLADDER (OAB) PATIENT’S URINE NERVE GROWTH FACTOR LEVEL (NGF) WITH THE DEGREE OF OVERACTIVE BLADDER’S SYMPTOM

Abstract

Overactive bladder (OAB) are conditions of urinary urgency with or without incontinence symptomps, and are usually followed with frequency and nocturia. OAB’s primary mechanism is inflammation in the bladder, with proof of nerve damage from inflammation in the bladder, enhancing secretion of Nerve Growth Factor (NGF). NGF is involved as chemical mediator from pathologic changes induced by stimuli to Afferent Nerve C and reflex from the bladder. New researchs are focused to find tools that are more effective and simple to detect OAB and assessing the degree of severity as sson as possible, one of the being the NGF levels in urine. Objective: To assess the correlation between OAB patient’s urine NGF with the severity degree of OAB Symptoms Method: This is a correlation analytic study with crossectional design, assessing OAB patient’s urine NGF level with severity degree of OAB symptoms using Spearman test with confidence interval of 95%. Results: This study shows that OAB patients have urine NGF level with mean 295,65 ± 69,898 pg/ml with NGF level increase along with the severity of symptoms. Median of 273.50 pg/mL with lowest 221 pd/mL and highest 525 pg/mL. According to correlation test, shows that there is significant positive strong correlation between Urine NGF with degree of symptom, assessed using OABSS with R = 0.796 and p = 0.001. Conclusion: There is significant positive strong correlation between Urine NGF with degree of symptom severity in OAB patients.

Key Words

NGF, overactive bladder

Cite This Article

"CORRELATION OF OVERACTIVE BLADDER (OAB) PATIENT’S URINE NERVE GROWTH FACTOR LEVEL (NGF) WITH THE DEGREE OF OVERACTIVE BLADDER’S SYMPTOM", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 1, page no.97-100, January-2020, Available :http://www.jetir.org/papers/JETIR2001015.pdf

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2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"CORRELATION OF OVERACTIVE BLADDER (OAB) PATIENT’S URINE NERVE GROWTH FACTOR LEVEL (NGF) WITH THE DEGREE OF OVERACTIVE BLADDER’S SYMPTOM", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 1, page no. pp97-100, January-2020, Available at : http://www.jetir.org/papers/JETIR2001015.pdf

Publication Details

Published Paper ID: JETIR2001015
Registration ID: 226770
Published In: Volume 7 | Issue 1 | Year January-2020
DOI (Digital Object Identifier):
Page No: 97-100
Country: Medan, Sumatera Utara, Indonesia .
Area: Medical Science
ISSN Number: 2349-5162
Publisher: IJ Publication


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