UGC Approved Journal no 63975(19)

ISSN: 2349-5162 | ESTD Year : 2014
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Published in:

Volume 7 Issue 2
February-2020
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR2002204


Registration ID:
227864

Page Number

17-23

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Title

MATRIX METALLOPROTEINASE 7 (MMP-7) LEVEL ON ATERM PREGNANCY ON PRIMIGRAVID AND MULTIGRAVID IN SERVICOVAGINAL FLUID

Abstract

In normal pregnancy, the human cervicovaginal fluid proteome is a picture of the local biochemical environment and is influenced by physical changes that occur in the vagina, cervix, and surrounding fetal membranes. Normal pregnancy is associated with hemodynamic signs and changes in the uterus followed by adequate uteroplacental blood flow and development of the uterus for fetal growth.3 Normal pregnancy is associated with significant uterine and vascular remodeling. Matrix metalloproteinase (MMP) is the main regulator of tissue remodeling. This shows that MMP plays a role in uteroplacental and vascular remodeling during normal pregnancy. This study is an analytical study using a cross sectional design to assess differences in MMP-7 levels in primigravid and multigravid pregnant women at delivery at the Adam Malik General Hospital in Medan and the USU FK network hospital. The study population was at term primigravid and multigravid pregnant women during labor in the delivery room, with samples of primigravid and multigravid pregnant women at delivery in the delivery room of the General Hospital. H. Adam Malik Medan and USU FK network hospital. Pregnant women who meet the research criteria as mentioned above, included in the subject of pregnancy during labor latent and active phase. It was found that an increase in MMP-7 level in primigravid and multigravid on latent and active phases, so it can be concluded that MMP-7 affects the duration of cervical maturation, the duration of the latent phase and the active phase in primigravid and multigravid, this indicates an increase in MMP-7 levels with (p <0.001), this indicates a significant relationship between increased levels of MMP-7 with cervical maturation and the duration of the latent and active phases in primigravid and multigravid.

Key Words

MMP-7, labor, latent phase, active phase

Cite This Article

"MATRIX METALLOPROTEINASE 7 (MMP-7) LEVEL ON ATERM PREGNANCY ON PRIMIGRAVID AND MULTIGRAVID IN SERVICOVAGINAL FLUID", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 2, page no.17-23, February-2020, Available :http://www.jetir.org/papers/JETIR2002204.pdf

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2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"MATRIX METALLOPROTEINASE 7 (MMP-7) LEVEL ON ATERM PREGNANCY ON PRIMIGRAVID AND MULTIGRAVID IN SERVICOVAGINAL FLUID", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 2, page no. pp17-23, February-2020, Available at : http://www.jetir.org/papers/JETIR2002204.pdf

Publication Details

Published Paper ID: JETIR2002204
Registration ID: 227864
Published In: Volume 7 | Issue 2 | Year February-2020
DOI (Digital Object Identifier):
Page No: 17-23
Country: Medan, North Sumatera, Indonesia .
Area: Medical Science
ISSN Number: 2349-5162
Publisher: IJ Publication


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