• M.PrashanthiEvangelin
• B.Gopi Krishna
• S.Yashita Raga
• Syed.Fathima
• P. Satya Durga Prasanna, Ch.Charitha,

Carvedilol is a third generation, non-selective, vasodilating β-blocker(β1,β2) mostly used in heart failure patients for the treatment of AMI(acute myocardial infarction), chronic heart failure,stable angina pectoris,Hypertension and also has selective α-blocking activity. It shows its therapeutic effect on cardio myocytes of heart by improving its contractile function.This drug also have anti-apoptotic, anti-bacterial (mostly gram positive), antiproliferative,and anti-inflammatory and antioxidant activities as the additional features.Methacrylic acid is the best molecular imprinted polymer for Carvedilol in the ratio 1:4.Innovations found that carvedilol is used in the treatment of arthritic joints by acting against collagen type- II and aggrecan in a dose dependent manner. Beyond all the above benefits of carvedilol our reviewliterature views on different procedures for the synthesis of effective carvedilol and it also enlists the impurities formed during its preparation

Carvedilol, Methacrylic acid, Anti-bacterial.

"BIO ACTIVE CARVEDILOL DERIVATIVES:A REVIEW", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 3, page no.681-693, March-2020, Available :http://www.jetir.org/papers/JETIR2003107.pdf

"BIO ACTIVE CARVEDILOL DERIVATIVES:A REVIEW", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 3, page no. pp681-693, March-2020, Available at : http://www.jetir.org/papers/JETIR2003107.pdf