• k.krishna
• M.meghana

Recently, a novel corona virus which officially called as severe acute respiratory syndrome coronavirus-2 of the genes Betacoronavirus and causative agent is COVID-19. according to world health organization declared that SARS-CoV2 is global pandemic(world wide spread of disease) on 12 march 2020.SARS-CoV2 which is first identified in the city of wuhan in china’s hubei province in December 2019, which is characterized as pulmonary infection . Therefore as the research was carried by the international authorities is that the patients should be diagnosis and rapid isolation should be done due to the lack of effective drug therapy. But due public health emergency it is made the sense to 4investigate a drug that shows possible effect of hydroxychloroquine against SARS-CoV2 . but the drug hydroxychloroquine is consider as part of an investigational protocol for the patients who are with COVID19 . therefore FDA approved hydroxychloroquine drug distribute millons of doses to hospitals across the country. hydroxychloroquine is the most potent inhibitor of these coronavirus .which have strong antiviral activity, and therefore inhibits the infection and spread of coronavirus. The drug hydroxychloroquine mainly shows immunomodulatory effect that is it is used to control the pro-inflammatory mediators (cytokines and interleukins) at the late phase of SARS-CoV2

Mechanism action of hydrochloroquinine

"Mechanism of hydrochloroquinine on SARS-COV2", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 4, page no.269-272, April-2020, Available :http://www.jetir.org/papers/JETIR2004038.pdf

"Mechanism of hydrochloroquinine on SARS-COV2", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 4, page no. pp269-272, April-2020, Available at : http://www.jetir.org/papers/JETIR2004038.pdf