• Rajeshri Bhimraj Shende,
• Dr.Vipul Patel

Inhalation is the best treatment of COPD (chronic obstructive pulmonary disease) and Asthma, The primary goal of inhalation therapy for local treatment is to reduce pulmonary symptoms, through the alleviation and/or prevention of airway inflammation and constriction. In this article inhalation was categorized by dosage form with the action in treatment on body organ. The phase of technological development accelerated in the 1950s, resulting in the refinement of delivery devices with two fundamentally different designs: pMDIs and DPIs. The evolution of pMDI was starting with the first CFC-pMDIs represented a real step forward in inhaler design, challenges remained in terms of device handling and drug delivery. Some patients found the sensation of the high-velocity cold plume produced by the CFC propellant unpleasant, and this contributed to poor inhaler technique. Inhalers using HFA rather than CFC propellants were developed, and the first HFA-pMDI was launched in 1994. In this review article gives details idea about pressurized metered dose inhaler (pMDI) components with formulation procedure and types of it. The article contains the operation mechanism of the meter dose inhaler and the evolutionary test in the mentioned in the guideline by FDA (Food Drug Administration) with their summary of the testing system. It also contains the guidelines generally followed by the industries for the development of a metered dose inhaler.

chronic obstructive pulmonary disease, metered dose inhaler, dry powder inhaler.

"A Review: General Concept About The Metered Dose Inhaler", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 4, page no.2130-2137, April 2020, Available :http://www.jetir.org/papers/JETIR2004494.pdf

"A Review: General Concept About The Metered Dose Inhaler", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 4, page no. pp2130-2137, April 2020, Available at : http://www.jetir.org/papers/JETIR2004494.pdf