UGC Approved Journal no 63975(19)

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Published in:

Volume 7 Issue 4
April-2020
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR2004524


Registration ID:
231224

Page Number

224-227

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Title

Assessment of prevalence of drug resistant Escherichia coli in Khan river, Indore

Abstract

Infectious diseases caused by antibiotic resistant bacteria (ARB) have emerged as a huge challenge globally, because of the difficulties associated with the treatments. ARB especially multidrug resistant (MDR) bacteria pose a significant threat to public health due to their high levels of resistance to most available antibiotics. Antibiotic resistance genes (ARGs) carried by bacteria may horizontally transfer to other bacteria. Polluted aquatic environments containing residual antibiotics may create a selective environment for the growth and spread of ARB in the environment. We have investigated the prevalence of antibiotic resistance in Escherichia coli population of Khan river, Indore. Water samples were collected from different sites of Khan river. Total heterotrophic bacterial (THB) counts were estimated. The samples were processed using standard protocols for the isolation and identification of E.coli. The bacterial isolates were further subjected to antibiotic susceptibility test for 13 different antibiotics by standard Kirby-Bauer disc diffusion method and the results were interpreted using Clinical and Laboratory Standards Institute (CLSI) criteria. The total heterotrophic bacterial (THB) counts were 1.8 X 106 – 1.2 X 1020 CFU/ml. Total 24 E.coli cultures were isolated from 09 water samples out of which 79.2% showed resistances to Ampicillin, followed by Cefadroxil (58.33%), Clarithromycin (54.16%), Cefuroxime (37.5%). The prevalence of resistance to Amoxicillin/clavulanic acid, Cefaclor, Nalidixic acid, Streptomycin, Gentamicin, Cefotaxime, Ciprofloxacin, Azithromycin and was 8.33% to 33.33%. Least resistance was observed against Cephoperazon (4.16%).

Key Words

Antibiotic resistance, Multidrug resistant (MDR), Antibiotic resistance genes (ARGs), Total heterotrophic bacteria (THB).

Cite This Article

"Assessment of prevalence of drug resistant Escherichia coli in Khan river, Indore", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 4, page no.224-227, April 2020, Available :http://www.jetir.org/papers/JETIR2004524.pdf

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2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"Assessment of prevalence of drug resistant Escherichia coli in Khan river, Indore", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 4, page no. pp224-227, April 2020, Available at : http://www.jetir.org/papers/JETIR2004524.pdf

Publication Details

Published Paper ID: JETIR2004524
Registration ID: 231224
Published In: Volume 7 | Issue 4 | Year April-2020
DOI (Digital Object Identifier): http://doi.one/10.1729/Journal.23556
Page No: 224-227
Country: Indore, Madhya Pradesh, India .
Area: Biological Science
ISSN Number: 2349-5162
Publisher: IJ Publication


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