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June-2020
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Journal of Emerging Technologies and Innovative Research ( An International Scholarly Open Access Journal, Peer-reviewed, Refereed Journal )
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UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975
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Published Paper ID:
JETIR2006429
Registration ID:
234625
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Title
METHOD DEVELOPMENT, VALIDATION OF STABILITY INDICATING LIQUID CHROMATOGRAPHIC METHOD AND FORCE DEGRADATION STUDY OF PYRIMIDINE DERIVATIVE
Authors
Abstract
An isocratic reversed phase stability-indicating high-performance liquid chromatographic (HPLC) assay method was developed and validated for quantitative determination of pyrimidine derivative and the simultaneous stability indicating study was carried out by using gradient pump system with the mobile phase Methanol/ Water (55/45) was selected to achieve maximum detection. SHIMADZU-HPLC, phenomenex C18, 250×4.6mm, 5µ column was used for the detection having flow rate 1ml/min, at 225 nm. The proposed method was found to be rapid, accurate and robust.
Key Words
HPLC method development, Stability indicating method, Pyrimidine Derivative.
Cite This Article
"METHOD DEVELOPMENT, VALIDATION OF STABILITY INDICATING LIQUID CHROMATOGRAPHIC METHOD AND FORCE DEGRADATION STUDY OF PYRIMIDINE DERIVATIVE", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 6, page no.626-638, June-2020, Available :http://www.jetir.org/papers/JETIR2006429.pdf
ISSN
2349-5162 | Impact Factor 7.95 Calculate by Google Scholar
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Cite This Article
"METHOD DEVELOPMENT, VALIDATION OF STABILITY INDICATING LIQUID CHROMATOGRAPHIC METHOD AND FORCE DEGRADATION STUDY OF PYRIMIDINE DERIVATIVE", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 6, page no. pp626-638, June-2020, Available at : http://www.jetir.org/papers/JETIR2006429.pdf
Publication Details
Published Paper ID: JETIR2006429
Registration ID: 234625
Published In: Volume 7 | Issue 6 | Year June-2020
Page No: 626-638
Country: -, -, - .
Area: Engineering
ISSN Number: 2349-5162
Publisher: IJ Publication
Published Paper URL :: https://www.jetir.org/view?paper=JETIR2006429
Published Paper PDF: https://www.jetir.org/papers/JETIR2006429
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