UGC Approved Journal no 63975(19)

ISSN: 2349-5162 | ESTD Year : 2014
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Published in:

Volume 7 Issue 6
June-2020
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR2006528


Registration ID:
234799

Page Number

1352-1355

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Title

Metastatic Malignant Melanoma of Rectum – A few and far between uncommonness

Abstract

INTRODUCTION: Malignant melanoma of rectum is an extremely rare and very aggressive neoplasm. It accounts for only 1% of anorectal malignancies and less than 1% of all melanomas. Patients often present with nonspecific complaints such as rectal bleeding, anal pain or change in bowel habit. Prognosis of malignant melanoma of rectum is very poor with a median survival of 24 months and a 5-year survival of 10-15%. CASE PRESENTATION: A 59-year-old male presented with a 10-month history of bleeding per rectum. MRI abdomen and pelvis revealed a 22 x 21 x 18 mm heterogeneously enhancing lesion over the right anterolateral wall of ano-rectum. Multiple enlarged mesorectal lymph nodes were seen. Right kidney showed two well-defined exophytic lesions of 15 x 12 mm and 12 x 9 mm and a well-defined soft tissue lesion of 36 x 26 x 25 mm in right suprarenal region. Patient underwent rectal polypectomy and the histopathology revealed malignant melanoma. On immunohistochemistry, S-100, HMB-45 and melan-A were positive. For adjuvant treatment, the patient was planned to receive dacarbazine and tamoxifen based chemotherapy. CONCLUSION: Malignant melanoma of rectum is an extremely rare and very aggressive neoplasm. Surgery remains the mainstay of treatment for limited disease. There are no standard solidarity recommendations for systemic therapy for disseminated disease. More research protocols & clinical trials should be explored to improvise survival in these patients.

Key Words

rectum melanoma, metastatic

Cite This Article

"Metastatic Malignant Melanoma of Rectum – A few and far between uncommonness", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 6, page no.1352-1355, June 2020, Available :http://www.jetir.org/papers/JETIR2006528.pdf

ISSN


2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"Metastatic Malignant Melanoma of Rectum – A few and far between uncommonness", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 6, page no. pp1352-1355, June 2020, Available at : http://www.jetir.org/papers/JETIR2006528.pdf

Publication Details

Published Paper ID: JETIR2006528
Registration ID: 234799
Published In: Volume 7 | Issue 6 | Year June-2020
DOI (Digital Object Identifier):
Page No: 1352-1355
Country: ROHTAK, HARYANA, INDIA .
Area: Medical Science
ISSN Number: 2349-5162
Publisher: IJ Publication


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