• Shilpa Laxman Sangle

Pyranopyrazole is a heterocyclic organic compound in which the pyran ring substituted by pyrazole in the ortho position. Pyranopyrazole can be synthesized by using Knoevenagel condensation, Michael’s addition, and cyclization reaction. Synthesis involves a multicomponent reaction of aldehyde, hydrazine, ethyl acetoacetate, and malononitrile as a precursors. These bioactive heterocycles has attracted the interest of medicinal and organic chemists due to their biological and medicinal properties. This review focuses on the recent developments in multicomponent synthesis of pyranopyrazole. The present review describes the literature reports for the period 2005 to 2018. These reported approaches were performed in the classical and nonclassical conditions, particularly recent reports includes protocols under a green condition such as using catalyst, green solvents, and solvent-free conditions.

multicomponent reactions; heterogeneous catalysts; pyranopyrazoles; one-pot process;

"REVIEW ON SYNTHESIS OF PYRANOPYRAZOLES DERIVATIVES", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 7, page no.1348-1353, July-2020, Available :http://www.jetir.org/papers/JETIR2007475.pdf

"REVIEW ON SYNTHESIS OF PYRANOPYRAZOLES DERIVATIVES", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 7, page no. pp1348-1353, July-2020, Available at : http://www.jetir.org/papers/JETIR2007475.pdf