• Dr. A.S. Suman Sankar
• Dr. C.K. Mohan
• Dr. N.V. Sugathan
• Dr. S.T. Gopukumar

Viral infections affect respiratory tract commonly, Most of the infections are mild and in some it would be severe with direct or indirect complications. Homoeopathic medicines are extensively used to treat influenza since long time. Several of those medicines have been possess anti-viral properties in ultra-diluted doses. Similarity in the pharmacodynamic properties and patient signs are the basis of Homoeopathic treatment. The curing property of these drugs is based on its disease causing property. Sanguinaria canadensis is one such important medicine used in Homoeopathy to treat influenza and its complications, both individually as well as in combination preparations. The signs and symptoms of most of the severe viral respiratory infections are similar to that of the drug proving observations on Sangunaria canadensis. The Sangunaraia respiratory symptoms are observed along with gastric and cardiac symptoms. The symptoms observed and recorded in Homoeopathic repertories are very similar to that of influenza like illness ranging from mild to severe respiratory illnesses. Secondary Metabolites action of Sangunaria canadensis displays antiviral activity impeding HIV protease. Protopine in addition to allocryptopine are more vigorous against Parainfluenza Virus-3. Sanguinarine is seen as the inhibitor of aminopeptidase A, dipeptidyl peptidase IV and aminopeptidase N. APN inhibitors could meddle in certain processes of the pathogenetic course of aggravation, tumor infiltration through the basal membrane and viral infection. Numerous plants produce Antiviral phyto-constituents which can target viral proteins, lipid envelope, and viral nucleic acids. DNA-intercalating drugs curb DNA and RNA polymerases and protein biosynthesis, and diminish viral replication. Fundamental oils and polyphenols are dynamic against the free infection, the intercalators can likewise repress the viral replication inside the host cell. Among the intercalating PSMs, alkaloids of the isoquinoline, quinoline and β-carboline type give a few incredible antiviral mixes to model. sanguinarine, in Sanguinaria canadensis is a solid DNA intercalator with articulated cytotoxic, antibacterial and antiviral properties. Homoeopathic dynamizations of Sanguinaria Canadensis are safe and has been successfully used for viral respiratory pneumonia for long time. This medicine in homoeopathy potencies could have a potential for inhibiting viral replication and disease progression. Based on the clinical experience gained from the use of Sanguinaria on viral respiratory illness and the adjuvant facts noted above, the potentized homoeopathic medicine Sanguinaria canadensis can be further studied for its application in severe viral respiratory illness like SARS Covid-2 as a stand-alone treatment or as an adjuvant treatment.

Aminopeptidase, Coronavirus Homeopathic, Influenza, Respiratory, Sangunaria Canadensis.

"SANGUINARIA CANADENSIS – A PROBABLE HOMOEOPATHIC MEDICINE FOR SEVERE VIRAL RESPIRATORY ILLNESS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 8, page no.718-726, August-2020, Available :http://www.jetir.org/papers/JETIR2008092.pdf

"SANGUINARIA CANADENSIS – A PROBABLE HOMOEOPATHIC MEDICINE FOR SEVERE VIRAL RESPIRATORY ILLNESS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 8, page no. pp718-726, August-2020, Available at : http://www.jetir.org/papers/JETIR2008092.pdf