• Gaurav Pandey
• Vinay Kumar Varshney
• Mandeep Kumar

Zinc oxide (ZnO) has attracted a great deal of interest because of its novel characteristics, especially when prepared in the nanometer regime. Due to its intensive luminescence, wide band gap (3.36 eV), and high exciton binding energy (60 meV), it has become a subject of great interest in nanoscience. Several methods have been established for synthesis of ZnO nanoparticles (ZnO NPs) with different shapes and properties. Nanoparticles of silver have been widely used as an antimicrobial and anticancer agent not only in industrial area including electronics and packaging, but also in medical areas. The continued interest of nano-ZnO has unleashed new synthetic methods such as physical, chemical, and green eco-friendly biological routes. Advanced characterization techniques like DLS, TEM, SEM, UV–VIS, XRD and ICP-MS are employed to investigate particle characteristics such as size, shape, and optical performance. ZnO NPs have effective activity against many microorganism and they also have selective cytotoxicity to the cancer cell. But there are fears as to their potential cytotoxic and genotoxic effects in human's cells: neurons and epithelial cells for instance. In this review we will show various methods of synthesis of ZnO NPs, the characterization in the light of antibacterial and cytotoxic effects on normal and cancer cells.

Zinc oxide nanoparticles (ZnO NPs), Chemical synthesis methods, Biosynthesis, Antibacterial activity, Antifungal activity, Nanotoxicology mechanisms

"Zinc Oxide Nanoparticles: Advances in Synthesis Routes, Antimicrobial Potential, and Mechanistic Insights into Toxicity", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 8, page no.77-91, August-2020, Available :http://www.jetir.org/papers/JETIR2008462.pdf

"Zinc Oxide Nanoparticles: Advances in Synthesis Routes, Antimicrobial Potential, and Mechanistic Insights into Toxicity", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 8, page no. pp77-91, August-2020, Available at : http://www.jetir.org/papers/JETIR2008462.pdf