• Mudita Mishra

The potential role of natural product have been identified for preventing or treating various diseases, our aim was to investigate The role of Alstonia scholaris leaves as anticancer. The phytochemical constituents of Alstonia sp. have been extensively investigated 2,3-secofernane triterpenoids, alstonic acids, were isolated from the leaves of Alstonia scholaris. first known examples of 2,3-secofernane triterpenoids. The plant Alstonia scholaris has a wide range of pharmacological activities. It is widely used in various traditional system of medicine as a medicine. It has been used since centuries as cooling agent, astringent, demulcent, appetizer; arthritis, tonic, aphrodisiac and in treatment of diarrhoea. Recent research carried out indicates its other uses such as antimicrobial, anti-fertility, anti inflammatory and antiemetic. The in vitro cytotoxic activity was performed by using MTT assay on Breast cell line T47D (organism- Homo sapiens, Human) and on breast cell line MCF 7 (organism- Homo sapiens, Human). Alstonia scholaris concentration (µg/ml) was increased, the % growth inhibition also increased.

MCF-7, Michigaen Cancer Foundation, MTT (3-(4, 5-dimethylthiazol-2-yl)-2,5-diphenyl tetra sodium bromide)

"PHARMACOGNOSTIC AND PHARMACOLOGICAL ACTIVITY OF ALSTONIA SCHOLARIS: A REVIEW", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 9, page no.985-996, September 2020, Available :http://www.jetir.org/papers/JETIR2009430.pdf

"PHARMACOGNOSTIC AND PHARMACOLOGICAL ACTIVITY OF ALSTONIA SCHOLARIS: A REVIEW", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 9, page no. pp985-996, September 2020, Available at : http://www.jetir.org/papers/JETIR2009430.pdf