• Dr. Rajnish Kumar
• Dr. Mehadi Imam
• Dr. Manoj Kumar Singh
• Dr. Mithilesh Kumar Singh

A series of 2-substituted naphtho[1,2-d]oxazole derivatives have been synthesized from 1-amino-2-naphthol hydrochloride as common substrate. For synthesis of 2-methylnaphtho[1,2-d]oxazole and 2-phenylnaphtho[1,2-d]oxazole we have employed carboxylic acid derivatives, namely acetic anhydride and benzoyl chloride respectively. Other 2-substituted naphto[1,2-d]oxazole derivatives have been synthesised from substituted aromatic aldehydes. In spite of evidences of solvent assisted thermal dehydrogenation of dihydroxazole ring, we have employed DDQ for dehydrogenation. All these compounds were characterized by FT-IR, ‘HNMR and elemental analysis.

Naphthoxazole, heterocyclic synthesis, DDQ, Biological properties.

"Synthesis and characterization of 2-substituted naphto[1,2-d]oxazole derivatives", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 10, page no.1761-1768, October-2020, Available :http://www.jetir.org/papers/JETIR2010228.pdf

"Synthesis and characterization of 2-substituted naphto[1,2-d]oxazole derivatives", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 10, page no. pp1761-1768, October-2020, Available at : http://www.jetir.org/papers/JETIR2010228.pdf