UGC Approved Journal no 63975(19)

ISSN: 2349-5162 | ESTD Year : 2014
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Published in:

Volume 7 Issue 10
October-2020
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR2010360


Registration ID:
302632

Page Number

2766-2780

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Title

Preparation and Evaluation of Solid-Self-Emulsifying Drug Delivery System Containing Olmesartan Medoxomil by using Capmul MCM-E8, Tween-80 and PEG 200

Abstract

Solubility of orally administered drug is major challenge of pharmaceutical industry as nearly 35-40% of newly launched drugs possess low aqueous solubility which leads to their poor dissolution and low bioavailability, resulting in high intra & inter subject variability & lack of dose proportionality. This can be increased by different methods like salt formation, solid dispersion and complex formation. Self-Emulsifying Drug Delivery System is gaining popularity for improving the solubility of lipophilic drugs. SEDDS are defined as isotropic mixtures of one or more hydrophilic solvents and co-solvents/surfactants that have a unique ability of forming fine oil-in-water (o/w) micro emulsions upon mild agitation followed by dilution in aqueous media, such as GI fluids. Present review provides an updated account of advancements in SEDDS with regard to its composition, evaluation, different dosage forms and newer techniques to convert liquid SEDDS to solid and also various applications.

Key Words

Preparation and Evaluation of Solid-Self-Emulsifying Drug Delivery System Containing Olmesartan Medoxomil by using Capmul MCM-E8, Tween-80 and PEG 200

Cite This Article

"Preparation and Evaluation of Solid-Self-Emulsifying Drug Delivery System Containing Olmesartan Medoxomil by using Capmul MCM-E8, Tween-80 and PEG 200", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 10, page no.2766-2780, October-2020, Available :http://www.jetir.org/papers/JETIR2010360.pdf

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2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"Preparation and Evaluation of Solid-Self-Emulsifying Drug Delivery System Containing Olmesartan Medoxomil by using Capmul MCM-E8, Tween-80 and PEG 200", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 10, page no. pp2766-2780, October-2020, Available at : http://www.jetir.org/papers/JETIR2010360.pdf

Publication Details

Published Paper ID: JETIR2010360
Registration ID: 302632
Published In: Volume 7 | Issue 10 | Year October-2020
DOI (Digital Object Identifier):
Page No: 2766-2780
Country: -, -, - .
Area: Engineering
ISSN Number: 2349-5162
Publisher: IJ Publication


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