• Shivendra Kumar Singh
• Pratibha Singh
• Jyotsna Kumari

Abstract The present paper paper deals with antioxidant defense and histology of geophagus of polluted and non polluted pond at biharsharif. The livers of Geophagus were collected from both a nonpolluted site and a polluted site were analyzed for different antioxidant defenses, O2 consumption, thiobarbituric acid-reactive substance (TBARS) levels, and histological damage. Compared to controls (116.6 ± 26.1 nmol g-1), TBARS levels were enhanced at the polluted site With respect to enzymatic antioxidants, increased catalase The main histological damage observed in the hepatocytes from fish collected at the polluted site was characterized by heavy lipid infiltration. Fish collected at the end of spring showed higher O2 consumption, higher superoxide dismutase and glutathione S-transferase activities, and higher total and oxidized glutathione concentrations compared to the beginning of autumn. No seasonal changes were observed in catalase activities, glutathione or TBARS levels. Fish chronically exposed to relatively high pollution levels seem to be unable to set up adequate antioxidant defenses, probably due to severe injury to their hepatocytes. The higher antioxidant defenses found at the end of spring are probably related to the enhanced activities during high temperature periods in thermoconforming organisms.

Kew words ; Antioxidant defense, Histology, O2 consumption, Catalase.

"Study of antioxidant defense and histology of geophagus of Polluted and non Polluted pond at Biharsharif ,Nalanda.India.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 10, page no.2784-2786, October-2020, Available :http://www.jetir.org/papers/JETIR2010362.pdf

"Study of antioxidant defense and histology of geophagus of Polluted and non Polluted pond at Biharsharif ,Nalanda.India.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 10, page no. pp2784-2786, October-2020, Available at : http://www.jetir.org/papers/JETIR2010362.pdf