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October-2020
eISSN: 2349-5162
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Journal of Emerging Technologies and Innovative Research ( An International Scholarly Open Access Journal, Peer-reviewed, Refereed Journal )
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UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975
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JETIR2010388
Registration ID:
302715
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Title
RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR ESTIMATION OF CHLORPHENIRAMINE MALEATE IN LIQUID DOSAGE FORM
Abstract
A high performance thin layer chromatographic method was developed and validated for determination for Chlorpheniramine maleate which comply with ICH Guidelines. The chromatographic development was performed using a Hypersil CN C18,(250×4.6mm, 5.0μm particle size) and a mobile phase composed of sodium dihydrogen o-phosphate buffer:Acetonitrile:Methanol (35:34:31 v/v/v), pH 6.2 adjusted with triethylamine at 1.3 ml/min flow rate.
The retention factor (Rf) was found to be 7.65 min.The linear calibration curves at concentration range 80-120% (r2 =0.9999) for Chlorpheniramine maleate.
Key Words
RP-HPLC Method.
Cite This Article
"RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR ESTIMATION OF CHLORPHENIRAMINE MALEATE IN LIQUID DOSAGE FORM", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 10, page no.2965-2971, October-2020, Available :http://www.jetir.org/papers/JETIR2010388.pdf
ISSN
2349-5162 | Impact Factor 7.95 Calculate by Google Scholar
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Cite This Article
"RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR ESTIMATION OF CHLORPHENIRAMINE MALEATE IN LIQUID DOSAGE FORM", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 10, page no. pp2965-2971, October-2020, Available at : http://www.jetir.org/papers/JETIR2010388.pdf
Publication Details
Published Paper ID: JETIR2010388
Registration ID: 302715
Published In: Volume 7 | Issue 10 | Year October-2020
Page No: 2965-2971
Country: Pune, Maharastra, India .
Area: Pharmacy
ISSN Number: 2349-5162
Publisher: IJ Publication
Published Paper URL :: https://www.jetir.org/view?paper=JETIR2010388
Published Paper PDF: https://www.jetir.org/papers/JETIR2010388
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