UGC Approved Journal no 63975(19)

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Volume 7 Issue 10
October-2020
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR2010388


Registration ID:
302715

Page Number

2965-2971

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Title

RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR ESTIMATION OF CHLORPHENIRAMINE MALEATE IN LIQUID DOSAGE FORM

Abstract

A high performance thin layer chromatographic method was developed and validated for determination for Chlorpheniramine maleate which comply with ICH Guidelines. The chromatographic development was performed using a Hypersil CN C18,(250×4.6mm, 5.0μm particle size) and a mobile phase composed of sodium dihydrogen o-phosphate buffer:Acetonitrile:Methanol (35:34:31 v/v/v), pH 6.2 adjusted with triethylamine at 1.3 ml/min flow rate. The retention factor (Rf) was found to be 7.65 min.The linear calibration curves at concentration range 80-120% (r2 =0.9999) for Chlorpheniramine maleate.

Key Words

RP-HPLC Method.

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"RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR ESTIMATION OF CHLORPHENIRAMINE MALEATE IN LIQUID DOSAGE FORM", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 10, page no.2965-2971, October-2020, Available :http://www.jetir.org/papers/JETIR2010388.pdf

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2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR ESTIMATION OF CHLORPHENIRAMINE MALEATE IN LIQUID DOSAGE FORM", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 10, page no. pp2965-2971, October-2020, Available at : http://www.jetir.org/papers/JETIR2010388.pdf

Publication Details

Published Paper ID: JETIR2010388
Registration ID: 302715
Published In: Volume 7 | Issue 10 | Year October-2020
DOI (Digital Object Identifier):
Page No: 2965-2971
Country: Pune, Maharastra, India .
Area: Pharmacy
ISSN Number: 2349-5162
Publisher: IJ Publication


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