UGC Approved Journal no 63975(19)

ISSN: 2349-5162 | ESTD Year : 2014
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Published in:

Volume 7 Issue 11
November-2020
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR2011384


Registration ID:
303763

Page Number

771-776

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Title

Formulation And Evaluation Of Antiemetic H. spicatum Lozenges

Abstract

Hedychium spicatum also called as Kapoorkachri or Shati is a rhizomatous, fragrant leafy herb with robust stem belonging to Zingiberaceae. Rhizomes have strong aromatic odour and bitter camphoraceous taste. Hedychium spicatum is traditionally used for its stimulant, carminative, stomachic and expectorant properties. Shati rhizomes have mention in Ayurvedic text for its use in Hairloss, Digestion and Respiratory problems, Cleansing Teeth, Cardiac Health , Headache, Joint pain and Hiccups. Rhizomes are usually used in the form of powder or formulated in syrups or tablets. Rhizome is reported to contain sitosterol and its glucosides, P-methoxy cinnamic acid ethyl ester, furanoid diterpene-hedychenone and 7- hydroxy hedychenone and essential oil contains Cineole, terpinene, limonene, phellandrene, p-cymene, linalool and terpeneol which contribute to its activity. Paediatric patients have low patient compliance towards drug formulations like tablets because of unpalatable taste . On the other hand, children can easily accept and swallow sweet lozenge with additive flavour. In order to provide better patient compliance we have formulated lozenges using shati rhizome extract specially for paediatric patients. Aim of this study involves design, preparation and evaluation of medicated lozenges. Methodology includes extraction of drug with cold maceration method using aqueous : ethanolic extract (1:1) proportion .Lozenge base was made with Sugar and corn syrup followed by addition of drug extract. Ginger juice was added as natural flavour and for additive antiemetic and antitussive property .Lozenges were made by casting method where in the resultant hot mix was poured in moulds. This lozenges are evaluated by pharmaceutical methods like moisture content, friability test, disintegration test which complies with IP.

Key Words

Hedychium spicatum, antiemetic, paediatric, Ayurvedic text

Cite This Article

"Formulation And Evaluation Of Antiemetic H. spicatum Lozenges", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.7, Issue 11, page no.771-776, November-2020, Available :http://www.jetir.org/papers/JETIR2011384.pdf

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2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"Formulation And Evaluation Of Antiemetic H. spicatum Lozenges", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.7, Issue 11, page no. pp771-776, November-2020, Available at : http://www.jetir.org/papers/JETIR2011384.pdf

Publication Details

Published Paper ID: JETIR2011384
Registration ID: 303763
Published In: Volume 7 | Issue 11 | Year November-2020
DOI (Digital Object Identifier):
Page No: 771-776
Country: Pune, Maharashtra, India .
Area: Pharmacy
ISSN Number: 2349-5162
Publisher: IJ Publication


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