UGC Approved Journal no 63975(19)

ISSN: 2349-5162 | ESTD Year : 2014
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Published in:

Volume 8 Issue 1
January-2021
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR2101334


Registration ID:
512034

Page Number

935-940

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Title

Comparative Modeling of Methionine S-adenosyltransferase a potential drug targeted protein of Mycobacterium

Abstract

Methionine S-adenosyltransferase plays a critical role in the active and dormant phases of mycobacterium life cycle which makes it an attractive antitubercular target. MAT is one of the 256 enzymes deemed necessary for the life. Mycobacterium tuberculosis (Mtb), causative organism of tuberculosis (TB), is a successful pathogen that overcomes the numerous challenges by the immune system of the host. In the last 40 years few drugs have been developed, while the drug resistance problem is increasing, there is thus a pressing need to develop new anti-TB drugs active against both the acute and chronic growth phases of the Mycobacterium. Methionine S-adenosyltransferase (MAT) is an enzyme involved in the synthesis of S-adenosylmethionine (SAM), a methyl donor essential for mycolipid biosynthesis. As an antiTB drug target, Mtb-MAT has been well validated.

Key Words

Comparative Modeling of Methionine S-adenosyltransferase a potential drug targeted protein of Mycobacterium

Cite This Article

"Comparative Modeling of Methionine S-adenosyltransferase a potential drug targeted protein of Mycobacterium", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 1, page no.935-940, January-2021, Available :http://www.jetir.org/papers/JETIR2101334.pdf

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2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"Comparative Modeling of Methionine S-adenosyltransferase a potential drug targeted protein of Mycobacterium", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 1, page no. pp935-940, January-2021, Available at : http://www.jetir.org/papers/JETIR2101334.pdf

Publication Details

Published Paper ID: JETIR2101334
Registration ID: 512034
Published In: Volume 8 | Issue 1 | Year January-2021
DOI (Digital Object Identifier):
Page No: 935-940
Country: -, -, India .
Area: Engineering
ISSN Number: 2349-5162
Publisher: IJ Publication


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