UGC Approved Journal no 63975(19)

ISSN: 2349-5162 | ESTD Year : 2014
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Published in:

Volume 8 Issue 2
February-2021
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR2102087


Registration ID:
305656

Page Number

743-751

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Title

ZnCl2 at MMT K-10 Catalysed Synthesis of 1,5-Benzodiazepine-2,4-diones from β-amino carbonyls

Abstract

1,5-benzodiazepine-2,4-diones are the most studied group of diazepine, which act as inhibitors of HIV-1 capsid assembly and reverse transcriptase. The benzodiazepine-2,4-dinone derivatives were prepared from β-amino carbonyl compounds by greener method using metal catalyst loaded on MMT K-10. The starting materials β-amino carbonyls were synthesized by multicomponent Mannich reaction at room temperature using 20 mol percentage of NH4Cl. Metal supported Montmorillonite K10-catalyzed reactions of various substituted β-amino carbonyls with OPDAs afforded 1,5-bezodiazapine-2,4-diones. Among the synthesized catalysts, the 10% Zn-K10 exhibited high conversion up to 90% and high selectivity up to 100% towards 1,5-bezodiazapine-2,4-diones

Key Words

β-aminocarbonyls, 1,5 –benzodiazepine, MMT-K-10, impregnation method, OPDAs

Cite This Article

"ZnCl2 at MMT K-10 Catalysed Synthesis of 1,5-Benzodiazepine-2,4-diones from β-amino carbonyls", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 2, page no.743-751, February-2021, Available :http://www.jetir.org/papers/JETIR2102087.pdf

ISSN


2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"ZnCl2 at MMT K-10 Catalysed Synthesis of 1,5-Benzodiazepine-2,4-diones from β-amino carbonyls", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 2, page no. pp743-751, February-2021, Available at : http://www.jetir.org/papers/JETIR2102087.pdf

Publication Details

Published Paper ID: JETIR2102087
Registration ID: 305656
Published In: Volume 8 | Issue 2 | Year February-2021
DOI (Digital Object Identifier):
Page No: 743-751
Country: PUNE, MAHARASHTRA, India .
Area: Chemistry
ISSN Number: 2349-5162
Publisher: IJ Publication


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