• Deepak Sameer Bind
• Dr.Vikas Mishra
• Dr.R.Sujatha
• Dr.Nashra Afaq

INTRODUCTION:-Gallstone disease is one of the most common disease affecting the gastrointestinal tract. Biliary tract infection results from bile stasis due to chronic obstruction, mainly (80%) gallstones. Biliary obstruction increases ductal pressure, resulting in bacterial proliferation and dissemination. AIM:- To study the Bacteriological profile of bile and its antimicrobial susceptibility and post-operative outcomes in cholecystectomy patients. MATERIAL & METHODS:- This prospective study included patients admitted in surgery department with a diagnosis of symptomatic gallstone disease and subjected for laparoscopic or open cholecystectomy between 1st of Jan 2019 to 30th December 2019. The intraoperative bile of patients subjected for cholecystectomy were cultured aerobically according to standard protocol. And the Antibiotics susceptibility testing was performed according CLSI guidelines 2019. RESULTS:¬- Out of the total 100 patients, bile culture was Positive in 10 patients. E.coli was the predominant isolate (6%) followed by S. lugdinensis (2%), and Acinetobacter spp (2%). The most sensitive antibiotic was Gentamicin (100% sensitivity) followed by Ciprofloxacin (80% sensitive) both in GNB and gram positive isolates, Vancomycin and Linezolid were the most effective showing 100% sensitivity CONCLUSION:- In this study E.coli was predominant bacteria causing recurrent cholecystitis. The common factor inducing infection was gall stone.

Cholecystectomy, E.coli, bile

"BACTERIOLOGICAL ANALYSIS OF BILE AND POST OPERATIVE OUTCOME IN CHOLECYSTECTOMY PATIENTS AT A TERTIARY CARE HOSPITAL IN KANPUR", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 3, page no.2299-2304, March-2021, Available :http://www.jetir.org/papers/JETIR2103287.pdf

"BACTERIOLOGICAL ANALYSIS OF BILE AND POST OPERATIVE OUTCOME IN CHOLECYSTECTOMY PATIENTS AT A TERTIARY CARE HOSPITAL IN KANPUR", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 3, page no. pp2299-2304, March-2021, Available at : http://www.jetir.org/papers/JETIR2103287.pdf