• Dnyaneshwar Sawairam Rathod

Abstract In this study, trial has been made to verify the toxicity of dimethoate on histopathological alteration in the liver of fish, Arius Dussumieri. First lethal and Sublethal concentration of dimethoate against the test fish ( LC50 is 5.99 and 1/10 of LC50 0.599 ) respectively was obtained. The laboratory acclimatized fishes were exposed to lethal and sublethal concentration of toxicant dimethoate and observed after 24 hours to 96 hours. Liver exposed to sublethal concentration of dimethoate showed significant changes compared to control structure of liver. There was hypertrophy of hepatic cells and the cells were disorganized, finally forming homogenous mass, loss of polygonal shape of hepatocytes, loss of liver cord orientation, breakdown of sinusoids. Fragmentation of nuclei, cell without nuclei and granular cytoplasm of the hepatocytes were observed in liver of exposed fish.

Key Words: LC50, Histopathology, Dimethoate, Arius Dussumieri.

"Dnyaneshwar Sawairam Rathod", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 3, page no.36-42, March-2021, Available :http://www.jetir.org/papers/JETIR2103395.pdf

"Dnyaneshwar Sawairam Rathod", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 3, page no. pp36-42, March-2021, Available at : http://www.jetir.org/papers/JETIR2103395.pdf