• Faruk Yusuf

Abstract: Diabetic peripheral nephropathy (DPN) may be a common chronic complication of diabetes mellitus. It results in distressing and expensive clinical sequelae like foot ulceration, leg amputation, and neuropathic pain (painful-DPN). Unfortunately, DPN is usually diagnosed late when irreversible nerve injury has occurred, and its first presentation is also with a diabetic foot ulcer. Several novel diagnostic techniques are available which can supplement clinical assessment and aid the first detection of DPN. Moreover, treatments for DPN and painful-DPN are limited. Only tight glucose control in type 1 diabetes has robust evidence in reducing the danger of developing DPN. However, neither glucose control nor pathogenetic treatments are effective in painful-DPN and symptomatic treatments are often inadequate. It’s recently been hypothesized that using various patient characteristics it should be possible to stratify individuals and assign them targeted therapies to provide better pain relief. We review the diagnostic techniques which can aid the first detection of DPN within the clinical and research environment, and recent advances in precision medicine techniques for the treatment of painful-DPN.

Diabetes mellitus (DM), Diabetic peripheral nephropathy (DPN), Sensory, Motor, Autonomic

"DIABETIC NEUROPATHY AND ITS TREATMENT: A NEUROLOGICAL DISEASE", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 5, page no.a49-a58, May-2021, Available :http://www.jetir.org/papers/JETIR2105135.pdf

"DIABETIC NEUROPATHY AND ITS TREATMENT: A NEUROLOGICAL DISEASE", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 5, page no. ppa49-a58, May-2021, Available at : http://www.jetir.org/papers/JETIR2105135.pdf