• Nidhi Kaushik
• Komal Chauhan
• Manjeet Aggarwal
• Rakesh Kumar Khandal

The present in vivo study deals with assessing the anti-diabetic potential of two millet varieties: Kodo and Kutki on wistar rats induced with diabetes by injecting (45 mg/kg body weight of rat) a freshly prepared solution of streptozotocin. Five different groups of rats were chosen: I) Normal control; fed with normal basal diet, II) Diabetic Control, diabetic rats but fed with normal diet, III) diabetic rats medicated with the anti-diabetic medicine: glibenclamide (5 mg/kg body weight) and fed with basal diet, IV) diabetic rats, fed with diet based on Kodo and V) diabetic rats, fed with diet based on Kutki, The diabetic rats (group III) were fed with anti-diabetic medicine while rats of the group (IV) and (V) were fed with a diet based on Kodo and Kutki respectively for 60 days. Glucose levels of rats of groups (IV) and (V) registered significant reduction, while certain biochemical changes indicated that rats were getting to towards their normal health parameters (P < 0.05). Examination of the pancreas, liver, stomach, heart, brain, and kidneys revealed that the rats (group IV and V) were as good as those of group (III). Both Kodo and Kutki exhibited effects similar or as good as anti-diabetic medicine. Rats of the group (IV) and (V) were found to be even healthier than rats (group, III), on basal diet. Thus, Kodo and Kutki showed an anti-hyperglycemic potential to control diabetes.

anti-diabetic, in vivo, Kodo, Kutki, Nutraceutical, Streptozotocin

"STUDIES ON WISTAR RATS TO ASCERTAIN ANTI-DIABETIC POTENTIAL OF KODO AND KUTKI MILLET", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 5, page no.c286-c302, May-2021, Available :http://www.jetir.org/papers/JETIR2105292.pdf

"STUDIES ON WISTAR RATS TO ASCERTAIN ANTI-DIABETIC POTENTIAL OF KODO AND KUTKI MILLET", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 5, page no. ppc286-c302, May-2021, Available at : http://www.jetir.org/papers/JETIR2105292.pdf