UGC Approved Journal no 63975(19)

ISSN: 2349-5162 | ESTD Year : 2014
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Published in:

Volume 8 Issue 5
May-2021
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR2105309


Registration ID:
309189

Page Number

c418-c428

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Title

TITLE: FORMULATION DEVELOPMENT AND EVALUATION OF GABAPENTIN IMMEDIATE RELEASE TABLETS

Abstract

Immediate release tablets of Gabapentin were successfully formulated by employing direct compression method. Preformulation studies of drug were performed; the infrared spectral analysis revealed that there is no chemical interaction with excipients used was compatible with drugs. Based on Weight variation, Hardness, friability, and Drug Content it was found that all the formulation were satisfied mention criteria as per Pharmacopoeial Standards. Disintegration time in F13 formulation found 17 sec and dispersion time found 15 sec. The in vitro drug release was 99 %. Overall, in the formulations prepared by direct compression method, F13 which contain 4 % CCS as Super disintegrants releases 99 % drug in 2 minutes was found the best formulation. Stability study of F13 batch was found stable for 1 month.

Key Words

Gabapentin, Weight variation, Disintegration time ,Immediate release tablets.

Cite This Article

"TITLE: FORMULATION DEVELOPMENT AND EVALUATION OF GABAPENTIN IMMEDIATE RELEASE TABLETS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 5, page no.c418-c428, May-2021, Available :http://www.jetir.org/papers/JETIR2105309.pdf

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2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"TITLE: FORMULATION DEVELOPMENT AND EVALUATION OF GABAPENTIN IMMEDIATE RELEASE TABLETS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 5, page no. ppc418-c428, May-2021, Available at : http://www.jetir.org/papers/JETIR2105309.pdf

Publication Details

Published Paper ID: JETIR2105309
Registration ID: 309189
Published In: Volume 8 | Issue 5 | Year May-2021
DOI (Digital Object Identifier):
Page No: c418-c428
Country: -, -, India .
Area: Engineering
ISSN Number: 2349-5162
Publisher: IJ Publication


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