• Vishal Prajapati
• Manoj Kumar Yadav
• Piyush Yadav
• Shashikant Maury
• Ravikant Vishwakarma

The term "drug design" refers to the process of developing new drugs with the aim of improving existing ones. Random screening of synthetic compounds, the synthesis of biologically active compounds based on naturally occurring drugs, the synthesis of structural analogues of naturally occurring lead molecules, and the application of the bioisosteric principle are only a few of the techniques that have been used. As a result, the most recent trend in drug development is to either completely reinvent a lead or optimise an established lead. The number of marine-derived items on the market has increased dramatically over the last decade. The sea is home to a diverse range of flora and fauna, the extracts of which have been shown to have therapeutic value in conditions such as cancer and macular degeneration. As a result, scientists are turning their attention away from synthetic substances and toward natural products. Drug production and testing, on the other hand, is a time-consuming operation. Researchers face obstacles at every stage of the process, from securing funding to obtaining good trial outcomes. Furthermore, due to global warming and human activities such as tourism and deforestation, the sea as a source is increasingly depleting. We've looked at a few promising marine compounds in this report. We've also included a few compounds that are currently being researched and may be beneficial to patients. This study also discusses the challenges that must be addressed in order to improve the success rate of marine drugs.

CADD, Marine Drug, Prototype, Analogues

"ROLE OF COMPUTER AIDED DRUG DESIGN IN MARINE DRUG DISCOVERY", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 5, page no.c968-c973, May-2021, Available :http://www.jetir.org/papers/JETIR2105378.pdf

"ROLE OF COMPUTER AIDED DRUG DESIGN IN MARINE DRUG DISCOVERY", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 5, page no. ppc968-c973, May-2021, Available at : http://www.jetir.org/papers/JETIR2105378.pdf