• Vijaya Laxmi Avula
• Mounika K
• Jyothi Thati
• Sailu Chintha

Background: Spherical Crystallization process incorporates crystallization and agglomeration simultaneously in one step. In this study benzoic acid agglomerates in spherical shape are prepared using anti solvent crystallization method with methanol-water-toluene system. Here benzoic acid is dissolved in methanol to prepare a saturated solution and this solution is added to water as an anti-solvent to crystallize the benzoic acid and 3rd solvent used to collect the individual crystals and agglomerate them. Under continuous agitation, the particles become spherical shaped agglomerates due to shear force. Result: In this work influence of temperature on spherical agglomeration of benzoic acid was studied and observed that with increasing temperature average agglomerate size was decreased. Particle size distribution and morphology improved with increasing process time at different temperatures. The total number of particles with residence time is calculated and found that the total number of particles decreased with increasing residence time, but become denser and bigger with time. Conclusion: In this work mainly solvent system has been changed and proven that it is possible to use different solvents as good solvent. kinetics has been found. Influence of temperature and processing time on Spherical crystallization of benzoic acid in Methanol - water -toluene system studied and found to have influence on the agglomerate growth. Kinetics has been found for the agglomerate growth rate and agglomeration process was described by first order kinetics.

Spherical Agglomeration, Crystallization, Morphology, Particle size.

"Effect of Temperature and Processing Time on Agglomerates Prepared by Spherical Crystallization", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 5, page no.e375-e383, May-2021, Available :http://www.jetir.org/papers/JETIR2105591.pdf

"Effect of Temperature and Processing Time on Agglomerates Prepared by Spherical Crystallization", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 5, page no. ppe375-e383, May-2021, Available at : http://www.jetir.org/papers/JETIR2105591.pdf