• R VIJAYALAKSHMI
• S KANCHANA
• J SANTHANALAKSHMI

In the present work green synthesis of copper oxide nano particles was carried out in the presence of aloe vera plant extract in aqueous medium at 45°C. Copper oxide nanoparticles in the as-synthesised conditions were size characterised by PXRD,HR-TEM and FE-SEM and was found to fall in the range 15+ 2.0 nm and such values coincided with reported values. The nano particles executed high stability and narrow polydispersity. The catalytic activity in the oxidation reactions of organic substrates was verified utilising 3- Indole derivatives.It was shown by many researchers that various indole derivatives have considerable anti-inflammatory, anti-microbial and anti-tumor activities which find potential therapeutic applications especially in the treatment of lung cancer. 3- indole carboxylic acid (ICA) and 3-(hydroxy acetyl) indole (IHA) were used as successful chemotherapeutic agents. However the results towards the shelf life ,longevity and in vitro activity stand needful. In this work oxidation reactions of 3-indole carboxylic acid (ICA ) and 3-(hydroxylacetyl) (IHA ) in presence of sodium peroxomono sulfate (Na2S2O5) as oxidant and CuO nps as the catalyst have been carried out at 25 0 C. Using the time variance UV absorption spectra recorded for each of the organic substrates ICA and IHA, the progress of the reactions were kinetically monitored and parameters such as half life period ( t½ ) and rate co-efficient (k) values were determined. The catalytic efficiency of CuO nps and IHA and ICA substrates were studied. It was found that CuO nps efficiently catalyzed the chosen indole derivatives and IHA reacted rapidly under oxidation stress more than ICA.

Metal oxide nano particle catalysis, CuO nano particles, 3-Indole derivatives.

"GREEN SYNTHESIS OF COPPER OXIDE NANO PARTICLES FROM ALOE VERA EXTRACT AND ITS CATALYTIC APPLICATIONS IN OXIDATION OF 3-INDOLE DERIVATIVES : A KINETIC STUDY", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 5, page no.f166-f175, May-2021, Available :http://www.jetir.org/papers/JETIR2105687.pdf

"GREEN SYNTHESIS OF COPPER OXIDE NANO PARTICLES FROM ALOE VERA EXTRACT AND ITS CATALYTIC APPLICATIONS IN OXIDATION OF 3-INDOLE DERIVATIVES : A KINETIC STUDY", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 5, page no. ppf166-f175, May-2021, Available at : http://www.jetir.org/papers/JETIR2105687.pdf