• Monali S.Jadhav
• Smita S.Aher

The present research work was carried out to develop a bilayer tablet of Ropinirole Hydrochloride. In this bilayer Ropinirole Hydrochloride IR layer and Ropinirole Hydrochloride SR layer was prepared and evaluated. The final bilayer tablet was formulated using optimized batch of Ropinirole Hydrochloride IR layer and Ropinirole Hydrochloride SR layer i.e. I8 and S9 respectively. The final bilayer tablet formulation (I8-S9) complied with the internal specification for weight variation, thickness, hardness, friability, drug content and in vitro drug release. The optimized formulation was compared with market product and showed better result as that of marketed formulation. After the stability study observed optimized batch shows no significant change in physical appearance, drug content or invitro dissolution pattern after storage at 40±2°C / 75±5%RH for 3months.

Keywords: Bilayer Tablet, Ropinirole, thickness, hardness, friability, drug content

"FORMULATION DEVELOPMENT AND EVALUATION OF BIPHASIC DRUG DELIVERY SYSTEM OF ROPINIROLE HYDROCHLORIDE.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 5, page no.g341-g353, May-2021, Available :http://www.jetir.org/papers/JETIR2105845.pdf

"FORMULATION DEVELOPMENT AND EVALUATION OF BIPHASIC DRUG DELIVERY SYSTEM OF ROPINIROLE HYDROCHLORIDE.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 5, page no. ppg341-g353, May-2021, Available at : http://www.jetir.org/papers/JETIR2105845.pdf