• Ms. Anjum Abbasi
• Dr. S.P. Subashini
• Ms. Simrat
• Ms.Pooja Saraswat

Background: In late December 2019 and on 1st January 2020, the coronavirus (COVID-19) infecting humans was first identified in Wuhan, Hubei Province, China. Later cases have also been confirmed worldwide. Coronaviruses are RNA viruses that are phenotypically and genotypically diverse. Globally, as of 6th April 2020, laboratory confirmed cases of COVID-19 reported to the World Health Organisation (WHO) amounted to 1 211 214, including 67 666 deaths. Aim: In the current study, we performed a literature review on coronavirus outbreak to summarise details about the pathogenesis, epidemiology, diagnosis and the man agement strategies for the disease control. Pathogenesis: Coronaviruses are tremendously precise and mature only in differ- entiated respiratory epithelial cells, as seen in both organ cultures as well as human volunteers. This virus will cause the antiviral T-cell response to be erratic, owing to the T-cell apoptosis activation, triggering the immune system to collapse.

corona, vaccine, virus, immunity, pandemic

"Coronavirus disease (COVID-19) pandemic: Its outbreak and current status ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 6, page no.a268-a282, June-2021, Available :http://www.jetir.org/papers/JETIR2106040.pdf

"Coronavirus disease (COVID-19) pandemic: Its outbreak and current status ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 6, page no. ppa268-a282, June-2021, Available at : http://www.jetir.org/papers/JETIR2106040.pdf