• Tushar Yadav
• Shashikant Maury
• Piyush Yadav
• Manoj Kumar Yadav
• Yadav Ashwani Kumar

ABSTRACT- Azadirachta indica, commonly known as neem, has attracted worldwide prominence in recent years, owing to its wide range of medicinal properties. Neem has been extensively used in Ayurveda, Unani and Homoeopathic medicine and has become a cynosure of modern medicine.Neem is an attractive broad-leaved, evergreen tree that can grow up to 30m tall and 2.5m in girth. Its trunk usually straight is 30-80 cm in diameter. Its spreading branches form a rounded crown of deep-green leaves and honey-scented flowers as much as 20m across. Azadirachtin is widely used as a basis for production of biopesticides; nevertheless, other properties have been recognized for this substance, among which the anticancer and antimalarial activity stand out. The methods available for azadirachtin extraction are diverse, including solid-liquid extraction and extraction with solvents at high or low temperatures. Alcohol based solvents are associated with higher extraction yields and are therefore preferred for the isolation of azadirachtin from plant parts. Clean-up of the extracts is generally required for further purification. The highest azadirachtin levels have been obtained from Neem seeds but concentration values present a large variation between batches. Therefore, in addition to extraction procedures, it is essential to establish routine methods for azadirachtin identification and quantification. Chromatography-based techniques are preferably selected for detection and quantification of azadirachtin in plant matrices. Overall, this process will guarantee a future reproducible, safe and effective use of the extracts in formulations for commercial applications.

KEYWORDS- Introduction, Taxonomical classification, Morphology, Sources, Macroscopical character, chemical constituents, MOA , Pharmacological implementation.

" A REVIEW ARTICLE ON: NEEM ( AZADIRACHTA INDICA) ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 6, page no.a649-a664, June-2021, Available :http://www.jetir.org/papers/JETIR2106087.pdf

" A REVIEW ARTICLE ON: NEEM ( AZADIRACHTA INDICA) ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 6, page no. ppa649-a664, June-2021, Available at : http://www.jetir.org/papers/JETIR2106087.pdf