• VIVEKANAND JADHAV

In the present protocol, a Sodium saccharin catalyst was utilized for the one-pot three-component cyclo condensation reaction of Aromatic Aldehyde, Barbituric acid, and dimedone, in water as environmentally benign water as a green medium at 80oC temperature within 30 minutes of reaction time in ethanol: water solvent system. The current method has major advantages like mild reaction conditions with a simple operation process, high yields, by using a less toxic and lower costlier catalyst.

"Sodium saccharin Mediated one-pot Synthesis of 2-amino-4H-Chromene Derivatives in Aqueous Media", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 7, page no.c662-c666, July-2021, Available :http://www.jetir.org/papers/JETIR2107357.pdf

"Sodium saccharin Mediated one-pot Synthesis of 2-amino-4H-Chromene Derivatives in Aqueous Media", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 7, page no. ppc662-c666, July-2021, Available at : http://www.jetir.org/papers/JETIR2107357.pdf