UGC Approved Journal no 63975

ISSN: 2349-5162 | ESTD Year : 2014
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Published in:

Volume 8 Issue 7
July-2021
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR2107565


Registration ID:
313039

Page Number

e477-e487

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Title

A SYSTEMATIC REVIEW ON SNAKE VENOM AND ITS THERAPEUTIC IMPLICATION

Authors

Abstract

Nature endowed snakes with a lethal secretion known as venom, which has been fine-tuned over millions of years of evolution. Snakes utilize venom to subdue their prey and to survive in their natural habitat. Venom is known to be a very poisonous mixture, consisting of a variety of molecules, such as carbohydrates, nucleosides, amino acids, lipids, proteins and peptides. Proteins and peptides are the major constituents of the dry weight of snake venoms and are of main interest for scientific investigations as well as for various pharmacological applications. These enzymes include metalloproteases (MP), disintegrins, L-amino acid oxidases (LAAOs), C-type lectins, and phospholipases A2 (PLA2s). Their mechanisms of action include direct toxic action (PLA2s), free radical generation (LAAOs), apoptosis induction (PLA2s, MP, and LAAOs), and antiangiogenesis (disintegrins and lectins). The functional specificity of peptides belonging to the same family can be attributed to subtle variations in their amino acid sequences. Currently, complementary tools and techniques are utilized to isolate and characterize the peptides, and study their potential applications as molecular probes, and possible templates for drug discovery and design investigations.

Key Words

Arterio-venous shunt; Bleeding risk; GPIIb/IIIa receptor; Platelet aggregation; Thrombosis.

Cite This Article

"A SYSTEMATIC REVIEW ON SNAKE VENOM AND ITS THERAPEUTIC IMPLICATION", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 7, page no.e477-e487, July-2021, Available :http://www.jetir.org/papers/JETIR2107565.pdf

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2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"A SYSTEMATIC REVIEW ON SNAKE VENOM AND ITS THERAPEUTIC IMPLICATION", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 7, page no. ppe477-e487, July-2021, Available at : http://www.jetir.org/papers/JETIR2107565.pdf

Publication Details

Published Paper ID: JETIR2107565
Registration ID: 313039
Published In: Volume 8 | Issue 7 | Year July-2021
DOI (Digital Object Identifier):
Page No: e477-e487
Country: patna, bihar, India .
Area: Science & Technology
ISSN Number: 2349-5162


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